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Cell 51, — Harris, S. Alzheimers Dis. He, Y. The Ccz1-Mon1-Rab7 module and Rab5 control distinct steps of autophagy. Cell 27, — Hjerpe, R. UBQLN2 mediates autophagy-independent protein aggregate clearance by the proteasome.

Cellular distribution of lysosomal hydrolase activities in the regenerating rat liver

Hofmann, K. A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems. Trends Biochem. Husnjak, K. Proteasome subunit Rpn13 is a novel ubiquitin receptor.


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Inestrosa, N. Psychiatry 1:e Itakura, E.

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 6, — Itzhaki, R. Jain, A. Jang, J. Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells. Stem Cells 32, — Jarome, T. CaMKII regulates proteasome phosphorylation and activity and promotes memory destabilization following retrieval.

Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala. Jiang, Y. Jung, T. The proteasome and the degradation of oxidized proteins: part III-Redox regulation of the proteasomal system. Redox Biol. Kabeya, Y. Cell Sci. Kakuta, S. Katzenell, S. Herpes simplex virus and interferon signaling induce novel autophagic clusters in sensory neurons.

Kawaguchi, Y. The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Keil, E. Khaminets, A. Ubiquitin-dependent and independent signals in selective autophagy. Trends Cell Biol. Kim, T. Herp enhances ER-associated protein degradation by recruiting ubiquilins. Kim, J. Kim, S. Psychiatry 21, — Kirkin, V.

Protein Turnover and Lysosome Function - 1st Edition

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Cell 33, — Kish-Trier, E. Structural biology of the proteasome. Komander, D. The ubiquitin code. Komatsu, M. Loss of autophagy in the central nervous system causes neurodegeneration in mice.

Ubiquitin Proteasome System programme

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Korolchuk, V. Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.


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    Autophagy and lysosomal proteolysis in the liver

    Lauritzen, I. Lee, D. Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery. EMBO Rep. Lee, Y. Cell Rep. Lee, J. HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. Lee, B. Enhancement of proteasome activity by a small-molecule inhibitor of USP Lee, M. Tau degradation: the ubiquitin-proteasome system versus the autophagy-lysosome system. Lee, S. Osmotic stress inhibits proteasome by p38 MAPK-dependent phosphorylation. Leib, D. Interaction of ICP Leissring, M. Implications for drug treatment and immunotherapy.

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